SCIENCE, RESEARCH, AND DATA ON E-CIGARETTES DOES EXIST

Latest Cardiology study says e-cigs lower heart and blood pressure rates

If you hear the phrase from anyone claiming they “can’t find science or research about e-cigarettes,” they aren’t looking hard enough, or they’re ignoring it. Dr. Konstantinos Farsalinos, a cardiologist, has continuously documented his research on e-cigarettes since 2011. He says e-cigarettes “result in huge potential benefits in the health of smokers.” Dr. Farsalinos is always looking for more data, and as research progresses, he’s confident it will help to improve the already safer and effective alternative to smoking. He also states regulation of e-cigarettes must be common sense and science-based.

SCIENCE, RESEARCH, AND DATA ON E-CIGARETTES DOES EXIST

New findings
For years, doctors have known smoking cigarettes causes an elevation in blood pressure and heart rates. In January, Dr. Farsalinos released clinical results on the effects of blood pressure and heart rates of e-cig users, adding to indisputable evidence that e-cigarettes are a less harmful alternative to smoking.

According to his latest study:

“Smokers who reduce or quit smoking by using EC (E-cigarettes) may lower their systolic BP (blood pressure) in the long term, and this reduction is particularly apparent in smokers with an elevated BP.”
“The use of low risk nicotine-containing products (including e-cigarettes) should be investigated as a safer alternative approach to harm reversal”
“The evidence-based notion that substitution of conventional cigarettes with ECs is unlikely to raise significant health concerns can improve counseling between physicians and their cardiovascular patients using or intending to use ECs.”

Dr. Farsalinos communicates
While some professionals in the public health sector decide to manipulate public opinion on existing research, Dr. Farsalinos not only performs research and science, he engages with consumers in the social media world. He will, on occasion, field questions and concerns of consumers and is forthright with his concerns of incoming data from other researchers. He has attended numerous conferences and presented evidence last year to the Federal Drug Administration.

Dr. Farsalinos continuously takes a responsible, proactive stance dedicating himself to the scientific side of e-cigarettes with regard to tobacco harm reduction. While his website, ecigarette-research.org is full of valuable information, Dr. Farsalinos is looking for more, and finding answers to questions about the safety and effectiveness of e-cigarettes in every sense of the word.

His message to consumers on bans?

“You should fight for your lives and your health. It is absolutely irresponsible and dangerous behaviour to ban e-cigarettes.” – Dr K Farsalinos.

Source: http://us.blastingnews.com/news/2016/02/science-research-and-data-on-e-cigarettes-does-exist-00797817.html

How to measure nicotine delivery from e-cigarettes

New protocol anticipates the EU Tobacco Products Directive, taking effect May 2016.
To be effective in helping smokers get off cigarettes, e-cigarettes need to deliver enough nicotine to replace what smokers were getting from tobacco, but also need to deliver it consistently at different use sessions. From later this year e-cigarettes sold in Europe will have to be tested to ensure that they deliver nicotine consistently, but no specific protocol has been proposed yet.

A new study published in the scientific journal Addiction evaluated a new method for measuring nicotine delivery from e-cigarettes. Researchers found that ‘first-generation’ e-cigarettes, which use ‘cartomizers’, delivered nicotine less consistently than later-generation e-cigarettes, which use ‘atomizers’ that vaporize e-liquid contained in a refillable tank. The consistency of nicotine delivery from the atomizers was similar to pharmaceutical nicotine inhalers and tobacco cigarettes and within the acceptable limits for medicinal nebulizers.

How to measure nicotine delivery from e-cigarettes

 

Three cartomizer and four tank-type atomizer products were tested, as well as three cartridges from a nicotine inhaler and three tobacco cigarettes.

The method requires the collection of three aerosol samples from 20-puff sessions (with a five-minute period between sessions) using the same cartomizer and the same wick-coil replacement head. The comparison between those puff sessions determines the intra-sample consistency. The same procedure is repeated twice, with the batteries fully charged, using two more cartomizers and wick-coil replacement heads. The comparison between the three cartomizers and between the three wick-coil replacement heads determines the inter-sample consistency.

The authors propose that this protocol could be adopted by the EU regulators as a method for testing consistency in nicotine delivery from e-cigarettes.

Source: http://www.addictionjournal.org/press-releases/how-to-measure-nicotine-delivery-from-e-cigarettes

E-cigarette as a Life Saver

Electronic cigarettes have been marketed as a device that could replace smoking. Despite the clashing ideas of whether this is true or not, the Ministry of Health in Britain has announced that e-cigarettes are less harmful than that of smoking. The main underlying reasons for this was that it does not involve smoke (which would then include fire) and also the point that it contains no tobacco. There have been many going against the idea of banning or regulating e-cigarettes mainly for the reason that vaporizers can save lives. Constant research and studies are being done regarding these devices in an attempt to pinpoint whether these devices are really harmful or not.
Viewing e-cigarettes as a method to save smokers has been a popular concept and it has helped many smokers to quit smoking. Jimmy Hafrey on ChurnMag.com (article: “Health Experts Say E-Cigs Could Save 50,000 Lives Each Year”), provides the information on a study done by health experts in Britain. “A London-based coalition of health experts are condemning the WHO (World Health Organization) remarks as misleading and arguing that ecigs could potentially revolutionize public health and save 50,000 lives per year in Britain alone” (Jimmy Hafrey).

E-cigarette as a Life Saver

The WHO has made the statement that e-cigarettes should be regulated because of the danger of e-cigarettes acting as a gateway to smoking and that there are toxins that are hazardous to health. The first point of e-cigarettes as a gateway to smoking is an argument that has been undermined through various research. Recent studies have shown that people who vape have been or are smokers with a mere 1% of non-smokers who have actually tried e-cigarettes. The latter statement of e-cigarettes being toxic has also been dented. E-cigarettes provide users with significantly less hazardous effects compared to that of conventional cigarettes. Obviously, the most idealistic situation would be one in which nobody smokes nor vapes. However, with the rise in popularity of e-cigarettes, there have been many that have or have made attempts to ban or regulate these products.
Banning these products may actually serve to deteriorate public health as people who initially made the switch to vaping may go back to their habit of smoking. “Based on current research data, scientists believe that for every one million smokers that switch to vaping, there are 6,000 premature deaths prevented per year. Using those calculations, if every smoker in England switched to ecigs, there would be 50,000 lives saved every year. With such incredible potential to stop smoking-related deaths, it seems absolutely ludicrous to caution people against vaping” (Jimmy Hafrey).
E-cigarettes have the potential to save lives. Eradicating smoking will not only save thousands of smokers but it will also save those who are exposed to second-hand smoking. Net Wellness (University of Cincinnati, The Ohio State University, Case Western Reserve University), has stated that “cigarette smoking causes an estimated 443,000 deaths each year, including approximately 49,000 deaths due to exposure to secondhand smoke. Lung cancer is the leading cause of cancer death among both men and women in the United States, and 90 percent of lung cancer deaths among men and approximately 80 percent of lung cancer deaths among women are due to smoking”. Smoking has thousands of chemicals and many of these are cancer causing chemicals. Lung cancer is only one of the many other cancers (throat, mouth, nasal, etc) that may occur due to smoking.
For some, this is the reason why it is so mind boggling that law makers would try to ban or regulate these products. With the rise in popularity for e-cigarettes, there has been a decrease in the population of smokers. If e-cigarettes were to be regulated, all those who quit smoking with the aid of vaporizers may return to their old habit of smoking. However, if e-cigarettes are regulated to the extent where it is available for those of age (especially smokers) and yet limited to minors, e-cigarettes have the potential to save millions of lives in the future.

Learn about the Truth

There has been a lot of confusion regarding the topic of e-cigarettes. It is no surprise that the public would be confused due to all of the contradicting information available on the internet. People get to choose which information that they would like to believe and based on this, they either support or are against vaping. However, a documentary has recently been released that talks about the truth about e-cigarettes. Jimmy Hafrey on ChurnMag.com introduces this documentary by saying that (article: “You Are Being Lied To: Documentary Exposes the Dirty Truth About the War on Vaping”) “Last summer, we told you about an upcoming documentary that was set to expose the true motives behind the anti-vaping agenda. Now we are approaching the official release of “A Billion Lives”, and a new clip offers a sneak peak at what you can expect from this highly anticipated film. Director Aaron Biebert’s goal is to expose the corruption that is threatening the vaping industry. While he isn’t a smoker (or vaper), he is taking up the cause because he believes organizations, health associations, and even government leaders are attacking vapor products to protect their own interests.

Learn about the Truth

There is too much at stake to let corruption eliminate the vapor industry. The World Health Organization estimates that a billion people will die in this century from smoking related causes. And vaping devices could be the key to turn it all around. Public Health England reports that “e-cigarettes are around 95 percent safer than smoked tobacco and they can help smokers to quit.” So why are government regulators and health experts constantly claiming that vaping is bad and could actually lead to increased tobacco use? It just doesn’t add up.
In “A Billion Lives”, Biebert will offer interviews with some of the world’s top health experts and leaders in the tobacco control sector. The film will get to the root of the war on vaping and expose the hidden motives behind the constant attacks. It will explore potential disruptions to tax revenue, pharmaceutical sales, and funding for government operated tobacco control programs. Ultimately, it will answer the questions that vape activists have been asking for years.
Vapers are calling this the most anticipated film of the year. It has the potential to turn things around and strip away the power of lying government leaders so that truth can prevail. Take a few minutes to watch this clip and then share it with your friends. You are being lied to, but it’s not too late to turn things around. It starts here…” (Jimmy Hafrey)
It is never too late to start. It is true that the damage has already been done as there are too many false information that many are believing on the media. However, as the old saying goes, “better now than never”. The conclusion on e-cigarettes seems to be getting closer and closer as more research and studies are being done. Many are now acknowledging the potential of e-cigarettes to save ultimately billions of lives of not only smokers but also of those who are exposed to second hand smoking. E-cigarettes show even more potential as the technology continues to advance. Advanced technologies are incorporated into vaporizers to ensure the users safety and to minimize any dangers that may occur. However, buyers must take caution to make sure that they are purchasing the original device and not a counterfeit. Counterfeit devices have shown to be dangerous and must not be trusted. Otherwise, the use of vaporizers show to be considerably less dangerous than smoking. Check out the video “A Billion Lives” and look into what they have to say about vaping!

Studying E-cigarettes

There has always existed the claim that there is a lack of information regarding e-cigarettes and that more studies need to be done in order to ensure the safety of these devices. So far, there have been multiple studies done and many point out that vaping is safer than smoking. Those who have claimed that it is just as dangerous as smoking has used unrealistic concentration of vape for their experiment and despite that, smoking still proved to be more dangerous. Now more studies are being carried out on the e-cigarette flavorings with the goal of determining whether these are safe or not.
Susan Murad on EurekAlert! (American Association for the Advancement of Science (AAAS)) has written an article on this which states that “Faculty and student researchers at Rochester Institute of Technology’s National Technical Institute for the Deaf (RIT/NTID) are developing methods to better analyze the effects of flavorings used in electronic cigarettes (e-cigs).
In partnership with RIT’s Kate Gleason College of Engineering and the University of Rochester Medical Center, RIT/NTID, the world’s first and largest technological college for deaf and hard-of-hearing students, is part of the team that has received a $329,000 grant from the National Institutes of Health to study the safety of e-cigs with flavorings.
E-cigs are increasing in popularity with both youth and adults, and a variety of flavorings often are present in these products. The presence of these flavorings may create health concerns to users and those around them due to lack of knowledge about their chemical make-up as they are being ingested and exhaled.

Studying E-cigarettes

Todd Pagano, associate professor and associate dean for Teaching and Scholarship Excellence, leads the NTID portion of the project along with a team of deaf and hard-of-hearing student researchers. Risa Robinson, professor and department head in Mechanical Engineering and director of the Respiratory Technologies Laboratory in RIT’s Kate Gleason College of Engineering, is the principal investigator on the RIT portion of the grant. The study is part of a larger project led by principal investigator Irfan Rahman of the University of Rochester Medical Center, whose aim is to examine the DNA damage and inflammatory responses of cells exposed to e-cigs.
“E-cigs, with their flavorings, are not regulated by the Food and Drug Administration and there is a deficiency in information on their possible impact on public health,” Pagano said. “Analyzing the potential toxicants produced by these flavorings will help increase the understanding of possible harmful effects of e-cig emissions.”
The project, “Emission aerosol constituents and comparative toxicology of electronic cigarettes with flavorings,” will determine the chemicals present in e-cigs emissions through the use of gas chromatography-mass spectrometry or GC-MS, a type of instrumentation present in many laboratory settings.
“The GC-MS provides analysis of the chemicals present in the e-cig liquid, and we are able to then measure the realistic exposure from produced constituents as they become emissions after vaping,” Pagano said. ‘We’re looking to determine what compounds are present before and after vaping, and which might be potentially harmful.'” (Susan Murad)
Hopefully this time they will actually undertake realistic experiments as they claim to give the public accurate information of the effects of vaping. It may be true that more information is needed about e-cigarettes to determine to determine the safety of these devices. However, it needs to be noted that they are still less dangerous than smoking. E-cigarette industries do not market their devices are being as safe as the air that we breathe and that is the reason that these devices are not to be sold to minors. These devices were developed mainly for smokers to use as an alternative to smoking. Using a less dangerous device would been improved public health for not only smokers but also for those around smokers who are exposed to second hand smoking. Though research is good, they need to be done in a correct manner using realistic examples to show accurate information about these devices.

Airway test reveals e-cigarette vapor produces similar result as air

E-cigarette vapour from two different types of e-cigarette had no cytotoxic impact on human airway tissue, according to new research published in Toxicology in Vitro (DOI: 10.1016/j.tiv.2015.05.018).

Scientists at British American Tobacco and MatTek Corporation used a unique combination of tests to investigate the potential adverse effects of e-cigarette vapour on airway tissue compared with cigarette smoke. ‘By employing a combination of a smoking robot and a lab-based test using respiratory tissue, it was possible to demonstrate the ability to induce and measure aerosol irritancy and to show that the different e-cigarette aerosols used in this study have no cytotoxic effect on human airway tissue,’ says spokesperson Dr Marina Murphy.

This new methodology could be used to help develop product standards for these kinds of products in the future.

E-cigarette vapour can contain nicotine, humectants, flavourings and thermal degradation products, so it is important to understand the potential impact on biological systems. Until now, there have been no aerosol studies of potential adverse effects of e-cigarette vapour on in vitro models that so closely mimic the structure, function and exposure of normal human airway tissue.

The researchers combined a commercially available 3D model of respiratory epithelial tissue and the popular VITROCELL smoking robot, an aerosol exposure system, to assess the irritant potential of e-cigarette vapour from two commercially available e-cigarettes on human airway tissue. The results show that, despite hours of aggressive and continuous exposure, the impact of the e-cigarette vapour on the airway tissue is similar to that of air. Furthermore, the study represents an initial move towards socialising and debating potential industrial guidelines.

The airway tissue model – EpiAirway – comprises human tracheal/bronchial epithelial cells that have been cultured to form differentiated layers resembling epithelial tissue of the respiratory tract. The VITROCELL system mimics the exposure when humans inhale by delivering emissions from cigarettes or e-cigarettes or just air to the EpiAirway tissues.

The researchers first tested the biological system with known irritants applied in liquid form. Then they exposed EpiAirway tissues to cigarette smoke or aerosol generated from two types of commercial e-cigarettes for up to six hours. During that time, cell viability was measured every hour using an established colorimetric test. The amount of particulate mass deposited on the cells’ surface was also quantified (using dosimetry tools) to prove that smoke or vapour had reached the tissue throughout exposure. The longer the time the cells were exposed, the bigger the dose they received in an incremental manner.

The results show that cigarette smoke reduces cell viability to 12% (near complete cell death) after six hours. In contrast, neither of the e-cigarette aerosols showed any significant decrease in cell viability. Despite 6 hours of continuous exposure, the results were similar to those of control cells exposed to only air. Even with this aggressive exposure, the e-cigarette vapours did not reduce cell viability.

‘Currently there are no standards concerning the in vitro testing of e-cigarette aerosols,’ said Marina Trani, Head of R&D for British American Tobacco’s next generation nicotine products. But, she adds, ‘our protocol could prove very useful in helping the process by which these guidelines might progress.’

This study shows that, in this human airway tissue model, cytotoxicity is unaffected by aerosols from two different types of e-cigarette, but further studies will be needed to compare the effects of other different commercially available products, formats and formulations.

This image shows the viability of human airway during aerosol exposure.

This image shows the viability of human airway during aerosol exposure.

Source: http://www.eurekalert.org/pub_releases/2015-07/raba-atr071415.php

Improvements from Vaping instead of Smoking

Though many have claimed that e-cigarettes are just as dangerous as smoking, this statement is absurd and highly exaggerated. The study that shows e-cigarettes to be dangerous is blown out of proportion and uses unrealistic examples by using unnatural concentrations of vapor. On the other hand, the dangers from smoking is a highly recognized idea that practically everybody is aware about. Jimmy Hafrey on ChurnMag.com elaborates on some of the improvements that one may gain from switching to vaping. His article (“Smokers Who Switch to Vaping Dramatically Improve Cardiovascular Health”) says that

“It’s no secret that smoking is bad for your heart. In fact, smokers are twice as likely to suffer heart attacks and they face increased risks for strokes and coronary heart disease. Research shows that smoking can actually damage the lining of your arteries, reduce the amount of oxygen in your blood, and force your heart to work harder just to maintain normal function. So what happens if you switch from smoking to vaping? According to the latest research, it can dramatically improve your cardiovascular health.
In a new study pioneered by Dr. Konstantinos Farsalinos, researchers recruited a group of smokers and offered them the chance to switch to vaping. Scientists monitored their progress for a full year. By the end of the study, some had completely quit smoking, others had reduced their cigarette use dramatically, and some had continued tobacco use with no major changes. Those who had completely switched to vaping or reduced their tobacco consumption by both smoking and vaping experienced major changes to their heart health.

Improvements from Vaping instead of Smoking
Many of the smokers had worrisome hypertension at the beginning of the study. But after switching completely to vaping, there was an average decline in systolic blood pressure of 16.3 mm Hg. Those who were dual users (both vaping and smoking) also lowered their blood pressure by an average of 10.8 mm Hg.
Perhaps most interesting of all, the researchers found that those who quit smoking and vaping completely had no further decrease in their blood pressure than those who ditched cigarettes and substituted with vaping. Ultimately, just by trading tobacco cigs for vapor devices, participants were able to continue the experience of smoking while experiencing dramatic benefits to their cardiovascular health.
This study is significant because it contradicts several previous misconceptions about vaping. Many health advocates have claimed that when smokers switch the vaping, they still experience increased cardiovascular risk because they still use nicotine. This study proves that this simply isn’t true.
Furthermore, it shows that vaping is in fact a legitimate alternative to smoking and it allows tobacco users a reasonable way to successfully kick the habit and improve their health dramatically. The study also offers proof that dual use is not necessarily the end of the world. We’ve heard vapor critics argue that dual use will only increase nicotine consumption, thereby doing more harm than good. However, this new study shows that even when smokers manage to cut their tobacco consumption in half by vaping, they still experience significant drops in blood pressure and cardiovascular risk.
Ultimately, this new study gives us just one more look at the potential ways that vaping can change the world. If vaping can help current smokers reduce their risk for heart attack and stroke, why isn’t every doctor in the world recommending this alternative?” (Jimmy Hafrey)

Vaping has been misrepresented by many and labeled in a incorrect way. Though it proves to be a device that will actually improve the health of those who switch, lawmakers are already in the final process of implementing regulations and bans regarding this device. The overall perception of e-cigarettes need to change to recognize vaporizers as an alternative to smoking that can save lives.

E-Cigarettes Could Be Behind Sharp Rise Of Successful Attempts To Quit Smoking

E-cigarettes could be behind the sharp increase in the number of people in England who have successfully quit smoking.

The Smoking Toolkit Survey which provides information about smoking and smoking cessation in England has released figures showing the success rate for people trying to quit smoking jumped from 14 percent in 2011 to 23 percent in 2016 – a rise of nine percentage points.

The increase is out of the ordinary, says Michael Siegel, a professor in the Department of Community Health Sciences, Boston University School of Public Health. According to Siegel, the rate of people successful quitting smoking in England remained steady from 2007 to 2011.

So what accounts for the sudden uptick in successful quitting?

According to Siegel, one of the strongest explanations is the surge in e-cigarette use over the past few years.

“Prior to 2011, virtually no smokers in England were using e-cigarettes to try to quit smoking, while approximately 30 percent were using NRT (Nicotine Replacement Therapy). By late last year, only about 10 percent of smokers were using NRT in quit attempts compared to about 40 percent using electronic cigarettes,” says Siegel.

E-Cigarettes Could Be Behind Sharp Rise Of Successful Attempts To Quit Smoking

Furthermore, there has also been no change in the overall number of percentage of smokers who are trying to quit tobacco. Sigel is in little doubt that the data demonstrates e-cigarettes have played a large part in helping people quit smoking as their use has become more common.

“These data add to the strong evidence that electronic cigarettes can help smokers quit. Based on this research, which includes a randomized trial of e-cigarettes compared to the nicotine patch, it seems clear that electronic cigarettes are at least as effective as nicotine replacement therapy and probably more so.”
Although not conclusive, the data will certainly give some anti-vaping activists pause for thought before making claims that e-cigarettes are not only ineffective for helping people quit but actually hurt people’s chances of getting off regular cigarettes.

A meta-analysis published in January purported to show that smokers who use e-cigarettes are in fact less likely to quit than those who don’t. This analysis was later subjected to a barrage of criticism from scientists and doctors who labelled it “unscientific.”

GUY BENTLEY
Reporter

Source: http://dailycaller.com/2016/02/16/e-cigarettes-could-be-behind-sharp-rise-of-successful-attempts-to-quit-smoking/

Misconception of E-cigarettes

As more information about e-cigarettes was beginning to spread across the media, the notion that e-cigarettes are not safe was brought about. The idea that e-cigarettes are just as harmful as smoking was popularized and caused many to hesitate and disregard e-cigarettes as an alternative to smoking. Though many of the rumors that claim e-cigarettes to be just as dangerous as smoking has been debunked, many still believe them to be as hazardous as smoking due to the vast amounts of media released regarding this matter. This shows how prone people are to media and how headlines themselves can change the opinion of many. Nikki Smith on Cancer Research UK (article title: “Headlines about e-cigarettes don’t mean they’re not safer than tobacco”), states that
“The first study to make the headlines suggested that e-cigarettes were ‘as harmful as tobacco’. After studying cells in the lab, the researchers found some indications of increased levels of DNA damage and cell death in those treated with e-cigarette vapour.
This led one of the researchers to tell the media, ‘I believe (e-cigarettes) are no better than smoking regular cigarettes.’
The most important thing to remember here is that this was a study looking at the effect of chemicals on cells in a lab. Although this can be useful, it obviously can’t give a clear idea of what the impact would actually be in your body. So any claims of impact on health based only on lab studies will always be far-fetched.
The study also looked at an extremely high concentration of vapour. As the researchers admitted at the time, ‘it was similar to someone smoking continuously for hours on end, so it’s higher amount than would normally be delivered.’
It boils down to this: the study showed that it might be worse for your cells to be exposed to e-cigarette vapour than the air in the lab. So e-cigarettes might not be 100 percent harm free. And previous studies have shown there may be some dangerous chemicals present in vapour – so this isn’t a surprise. And there’s little in life that really is ‘safe’ – even drinking too much water can kill you.
But here’s the big caveat. The researchers also treated some cells with tobacco smoke. These died within 24 hours. Those treated with e-cigarette vapour were still alive to experiment on 8 weeks later.
So, contrary to the headlines, this study actually suggests that using e-cigarettes may be far less dangerous than smoking” (Nikki Smith)

Misconception of E-cigarettes

Now, how many people are aware of this fact that the information about e-cigarettes are highly exaggerated and blown out of proportion? By reading the studies released by these scientists that do not clearly state that the experiment was carried out in an unrealistic scale of high concentrated vapor, it is only natural that the public would think of e-cigarettes as a dangerous tool that is no better than smoking. By trying to prevent people from vaping by labeling it as a device just as dangerous as smoking, such claims are now threatening the lives of thousands of smokers who could have switched to the less dangerous e-cigarettes. At the current moment, is not e-cigarette the better choice than conventional cigarettes? If one is not able to quit smoking, would it then not be better to vape?
Yes, it may be a controversial issue when it comes to the question of is this device safe. However, it is not a controversial issue when it comes down to measure if it is a less dangerous device compared to that of smoking. Vaping is less hazardous than smoking and many who have switched to vaping has experienced improvements in health. It is most recommendable that people quit smoking altogether but as this is not simply done, it would be better if they were to use e-cigarettes instead of conventional cigarettes.

Source:www.vaping360.com